1. Radák Z, Chung HY, Goto S: Systemic adaptation to oxidative challenge induced by regular exercise. Free Radic Biol Med 44: 153-159, 2008.
  2. Radák Z, Chung HY, Goto S: Systemic adaptation to oxidative challenge induced by regular exercise. Free Radic Biol Med 44: 153-159, 2008.
  3. Radák Z, Chung HY, Koltai E, Taylor AW, Goto S. Exercise, oxidative stress and hormesis. Ageing Res Rev 7: 34-42, 2008.
  4. Ji LL, Radák Z, Goto S: Hormesis and Exercise: How the cell copes with oxidative stress. Am J Pharmacol Toxicol 3: 41-55, 2008.
  5. Furusawa H, Sato Y, Tanaka Y, Inai Y, Amano A, Iwama M, Kondo Y, Handa S,Murata A, Nishikimi M, Goto S, Maruyama N, Takahashi R, Ishigami A. Vitamin C is not essential for carnitine biosynthesis in vivo: verification in vitamin C-depleted senescence marker protein-30/gluconolactonase knockout mice. Biol Pharm Bull. 31: 1673-1679, 2008.
  6. Hepple RT, Qin M, Nakamoto H, Goto S: Caloric restriction optimizes the proteasome pathway with aging in rat plantaris muscle: implications for sarcopenia. Am J Physiol Regulatory Integrative Comp Physiol 295: 1231-1237, 2008.
  7. 後藤佐多良:エイジングとアンチエイジングの分子機構概説. 臨床血液 49: 367-372, 2008.
  8. 後藤佐多良:抗酸化サプリメントの功罪とカロリー制限および運動の抗老化作用. 日本老年医学会雑誌 45: 155-158, 2008.


  1. Nakamoto H, Kaneko T, Tahara S, Hayashi E, Naito H, Radák Z, Goto S: Regular exercise reduces 8-oxodG in the nuclear and mitochondrial DNA and modulates the DNA repair activity in the liver of old rats. Exp Gerontol 42: 287-295, 2007.
  2. Goto S, Naito H, Kaneko T, Chung HY, Radák Z. Hormetic effects of regular exercise in aging: correlation with oxidative stress. Appl Physiol Nutr Metab. 32: 948-953, 2007.
  3. Goto S, Radák Z: Regular exercise attenuates oxidative stress in aging rat tissues: A possible mechanism toward anti-aging medicine. J Exer Sci Fit 5: 1-6, 2007.
  4. Radák Z, Kumagai S, Taylor AW, Goto S: Effects of exercise on brain functions: Role of free radicals. Appl Physiol Nutr Metabol. 32: 948-953, 2007.
  5. Radák Z, Kumagai S, Nakamoto H, Goto S. 8-Oxoguanosine and uracil repair of nuclear and mitochondrial DNA in red and white skeletal muscle of exercise-trained old rats. J Appl Physiol. 102:1696-1701, 2007.
  6. Odera K, Goto S, Takahashi R: Age-related change of endocytic receptors megalin and cubilin in the kidney in rats. Biogerontolgy 8: 505-515, 2007.
  7. Hashimoto AH, Amanuma K, Hiyoshi K, Sugawara Y, Goto S, Yanagisawa R, Takano H, Masumura K, Nohmi T, Aoki Y. Mutations in the lungs of gpt delta transgenic mice following inhalation of diesel exhaust. Environ Mol Mutagen. 48: 682-693, 2007.
  8. Li L, Shoji W, Takano H, Nishimura N, Aoki Y, Takahashi R, Goto S, Kaifu T,Takai T, Obinata M. Increased susceptibility of MER5 (peroxiredoxin III) knockout mice to LPS-induced oxidative stress. Biochem Biophys Res Comm 355: 715-721, 2007.
  9. Goto S, Takahashi R, Radák Z, Sharma R: Beneficial biochemical outcomes of late onset dietary restriction in rodents. Ann NY Acad Sci 1100: 431-441, 2007.
  10. 後藤佐多良:カロリー制限と運動の抗老化作用. 内分泌・糖尿病科 25: 616-620, 2007.
  11. 後藤佐多良:運動ホルミシスと抗老化. 基礎老化研究 31: 7-11, 2007.
  12. 田平武・後藤佐多良・大澤俊彦・倉地幸徳 2007年新春特別座談会「加齢・老化・アンチエイジングを考える」Vita (BML) 24: 3-22, 2007.
  13. 後藤佐多良:誌上ディベート:老年学とアンチエイジング 老化と抗老化を考える:基礎老化学からの視点. 日本抗加齢医学会雑誌 3: 58-62, 2007.


  1. Sharma R, Nakamura A, Takahashi R, Nakamoto H, Goto S: Carbonyl modification in rat liver histones: Decrease with age and increase by dietary restriction. Free Radic Biol Med 40: 1179-1184, 2006.
  2. Radák Z, Toldy A, Szabo Z, Siamilis S, Nyakas C, Silye G, Jakus J, Goto S. The effects of training and detraining on memory, neurotrophins and oxidative stress markers in rat brain. Neurochem Int 49:387-392, 2006.
  3. Kondo Y, Inai Y, Sato Y, Handa S, Kubo S, Shimokado K, Goto S, Nishikimi, Maruyama N, Ishigami A. SMP30 functions as gluconolactonase in L-ascorbic acid biosynthesis and its knockout mice are prone to scurvy. Proc Natl Acad Sci USA 103: 5723-5728, 2006.
  4. Goto S: Health span extension by later-life caloric or dietary restriction: a view based on rodent studies. Biogerontology 7:135-138, 2006.
  5. Sato T, Seyama K, Sato Y, Mori H, Souma S, Akiyoshi T, Kodama Y, Mori T, Goto S, Takahashi K, Fukuchi Y, Maruyama N, Ishigami A: Senescence marker protein-30 protects mice lungs from oxidative stress, aging and smoking. Am J Resp Crit Care 174: 530-537, 2006.
  6. Yasuda K, Ishii T, Suda H, Akatsuka A, Hartman PS, Goto S, Miyazawa M, Ishii N: Age-related changes of mitochondrial structure and function in Caenorhabditis elegans. Mech Ageing Dev 127: 763-770, 2006
  7. Reifschneider NH, Goto S, Nakamoto H, Takahashi R, Sugawa M,. Dencher NA, Krause F. Defining the mitochondrial proteomes from five rat organs in a physiologically significant context using 2D Blue-Native/SDS-PAGE. J Proteome Res. 5: 1117-1132, 2006.
  8. Dencher NA, Goto S, Reifschneider, Sugawa M, Krause F. Unraveling age-dependent variation of the mitochondrial proteome. Ann NY Acad Sci 1067: 116-119, 2006.
  9. Takahashi R, Komiya Y, Goto S: Effect of dietary restriction on learning and memory impairment and histologic alterations of brain stem in senescence-accelerated mouse (SAM) P8 strain. Ann New York Acad Sci 1067: 388-393, 2006.
  10. 後藤佐多良:特集「第18回国際老年学会におけるトピックス」Invited Symposium (Biological Sciences): Intervention of Aging and Age-Related Diseases (老化および老化関連病態への介入). ジェロントロジ−ニュ−ホライズン18: 19-22, 2006.
  11. 後藤佐多良:高齢社会における基礎老化学の役割. 日本老年医学会雑誌 43:289-292, 2006


  1. Goto S, Radák Z: Proteins and Exercise (Chapter 4) In: Molecular and Cellular Exercise Physiology (Ed. Mooren FC, V?lker K, Human Kinetics, USA, 2005) pp.55-70
  2. Radák Z, Goto S, Nakamoto H, Udud K Papai Z, Horvath I: Lung cancer in smoking patients inversely alters the activity of hOGG1 and hNTH1. Cancer Letters 219:191-195, 2005.
  3. Ogonovszky H, Berkes I, Kumagai S, Kaneko T, Tahara S, Goto S, Radák Z: The effects of moderate-, strenuous- and over-training on oxidative stress markers, DNA repair, and memory, in rat brain. Neurochem Int. 46: 635-640, 2005.
  4. Krause F, Reifschneider NH, Goto S, Dencher NA: Active oligomeric ATP synthases in mammalian mitochondria. Biochem Biophys Res Comm 329:583-590, 2005.
  5. Radák Z, Chung HY, Goto S: Opinion: Exercise and hormesis: Oxidative stress-related adaptation for successful aging. Biogerontology 6: 71-75, 2005.
  6. Ogonovszky H, Sasvari M, Dosek A Berkes I, Kaneko T, Tahara S, Nakamoto H, Goto S, Radák Z. The effects of moderate, strenuous, and overtraining on oxidative stress markers and DNA repair in rat liver. Can J App Physiol 30: 186-195. 2005.
  7. Kitani K, Goto S. Interview "My involvement in aging research was just a series of coincidences" An interview with Kenichi Kitani. Biogerontology 6:211-221, 2005.
  8. Goto S. Review: Mechanism and intervention of biological aging: A perspective from oxidative stress and metabolic turnover of proteins. J Soc Jap Women Scientists 6:7-15, 2005.
  9. 後藤佐多良:高齢医学におけるトランスレ−ショナル・リサ−チ. 基礎老化研究の応用を考える.日本老年医学会雑誌 42: 144-151, 2005.
  10. 後藤佐多良:老化の生物学的研究と老化制御 理大科学フォーラム 9: 33-38, 2005.
  11. 後藤佐多良:ホルミシスと老化介入−第一回国際ホルミシス会議International Conference on "Hormesis: Implications for Toxicology, Medicine and Risk Assessment" 参加記. 基礎老化研究29: 45-47, 2005.

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