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田中 光 ＜たなか ひかる＞ 東邦大学薬学部教授、薬学博士
 最新-2020 | 2019-2010 | 2009-2000 | 1999-1990 | 1989-  最新-2015  最新-2015  最新-2006
 最新-2020 | 2019-2010 | 2009-2000 | 1999-1992 | 1991-  
原著論文 2019年－2010年
2019
| 194) |
Yusuke Tanaka, Kae Obata, Tamano Ohmori, Kohei Ishiwata, Manato Abe, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka. Angiotensin Ⅱ induces automatic activity of the guinea pig pulmonary vein myocardium through activation of the IP3 receptor and the Na+-Ca2+-exchanger. Int. J. Mol. Sci. 20: 20: 1768 (2019) |
| 193) |
Masahiko Irie, Haruhito Hiiro, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka. Involvement of the persistent Na+ current in the diastolic depolarization and automaticity of the guinea pig pulmonary vein myocardium. J. Pharmacol. Sci. 141: 9-16 (2019) |
| 192) |
Naoki Agata, Yoshimitsu Kato, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka. Resistance of fetal guinea pig ventricular myocardium to hypoxia: maintained intracellular ATP prevents the opening of ATP-sensitive potassium channels. Biol. Pharm. Bull. 42: 268-272 (2019) |
| 191) |
Iyuki Namekata, Yusuke Tanaka, Tamano Ohmori, Yayoi Tsuneoka, Shogo Hamaguchi, Hikaru Tanaka. Cell morphology and early phase Ca2+ transients of guinea pig pulmonary vein cardiomyocytes compared with atrial and ventricular cardiomyocytes. Bioimages. 37:1-12 (2019) |
2018
| 190) |
Iyuki Namekata, Haruhito Hiiro, Haruna Kanae, Ayako Yoshino, Akihiro Kazama, Shogo Hamaguchi, Hikaru Tanaka. Acceleratory effect of ellagic acid on sarcoplasmic reticulum Ca2+ uptake and myocardial relaxation. Int. J. Hum. Cult. Stud. 28:701-707 (2018) |
| 189) |
Xin Cao, Megumi Aimoto, Marie Fukumoto, Yoshimitsu Nagasawa, Hikaru Tanaka, Akira Takahara. Influence of chronic volume overload-induced atrial remodeling on electrophysiological responses to cholinergic receptor stimulation in the isolated rat atria. J. Pharmacol. Sci. 136:73-78 (2018) |
2017
| 188) |
Kanae H, Hamaguchi S, Wakasugi Y, Kusakabe T, Kato K, Namekata I, Tanaka H. Pathological prolongation of action potential duration as a cause of the reduced alpha-adrenoceptor-mediated negative inotropy in streptozotocin-induced diabetic mice myocardium. J. Pharmacol. Sci. 135:131-133 (2017) |
| 187) |
Irie M, Tsuneoka Y, Shimobayashi M, Hasegawa N, Tanaka Y, Mochizuki S, Ichige S, Hamaguchi S, Namekata I, Tanaka H. Involvement of alpha- and beta-adrenoceptors in the automaticity of the isolated guinea pig pulmonary vein myocardium. J. Pharmacol. Sci. 133:247-253 (2017) |
| 186) |
Tsuneoka Y, Irie M, Tanaka Y, Sugimoto T, Kobayashi Y, Kusakabe T, Kato K, Hamaguchi S, Namekata I, Tanaka H. Permissive role of reduced inwardly-rectifying potassium current density in the automaticity of the guinea pig pulmonary vein myocardium. J. Pharmacol. Sci. 133:195-202 (2017) |
| 185) |
Namekata I, Hamaguchi S, Kusakabe T, Kato K, Tanaka H. Fluorescent analysis of the mitochondrial effect of a plasmalemmal Na+/Ca2+ exchanger inhibitor, SEA0400, in permeabilized H9c2 cells. Biol. Pharm. Bull. 40:1551-1555 (2017) |
| 184) |
Namekata I, Kanazawa A, Hamaguchi S, Tanaka H, Iida-Tanaka N. Fluorescence imaging-based analysis of the mitochondrial permeability transition pore opening in cardiomyocyte-derived H9c2 cells. Int. J. Hum. Cult. Stud. 27:14-19 (2017) |
| 183) |
Jin H, Fujita T, Jin M, Kurotani R, Namekata I, Hamaguchi S, Hidaka Y, Cai W, Suita K, Ohnuki Y, Mototani Y, Shiozawa K, Prajapati R, Liang C, Umemura M, Yokoyama U, Sato M, Tanaka H, Okumura S, Ishikawa Y. Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway. J. Mol. Cell. Cardiol. 108:170-180 (2017) |
2016
| 182) |
Hamaguchi S, Tsuneoka Y, Hikita K, Tanaka Y, Namekata I, Tanaka H. Enhancement of automaticity by mechanical stretch in the isolated guinea pig pulmonary vein myocardium. Biol. Pharm. Bull. 39:1216-1219 (2016) |
| 181) |
Nakamura Y, Sasaki R, Cao X, Wada T, Hamaguchi S, Izumi-Nakaseko H, Ando K, Tanaka H, Takahara A, Sugiyama A. Intravenous anti-influenza drug oseltamivir will not induce torsade depointes: Evidences from proarrhythmia model and action-potential assay. J. Pharmacol. Sci. 131:72-75 (2016). |
| 180) |
Namekata I, Kaeriyama S, Hamaguchi S, Iida-Tanaka N, Kawanishi T, Tanaka H. Mitochondrial membrane potential oscillations in isolated cardiomyocytes as revealed by fluorescence microscopy. Current Topics in Pharmacology. 20: 39-44 (2016) |
2015
| 179) |
Hamaguchi S, Tsuneoka Y, Tanaka A, Irie M, Tsuruta M, Nakayama T, Namekata I, Nada M, Aimoto M, Takahara A, Tanaka H. Manifestation of automaticity in the pulmonary vein myocardium of rats with abdominal aorto-venocaval shunt. J. Pharmacol. Sci. 128:212-215 (2015) |
| 178) |
Ikaga R, Namekata I, Kotiadis VN, Ogawa H, Duchen M, Tanaka H, Iida-Tanaka N. Knockdown of aquaporin-8 induces mitochondrial dysfunction in 3T3-L1 cells. Biochem. Biophys. Rep. 4:187-195 (2015) |
| 177) |
Namekata I, Hamaguchi S, Tanaka H. Pharmacological discrimination of plasmalemmal and mitochondrial sodium-calcium exchanger in cardiomyocyte-derived H9c2 cells. Biol.Pharm. Bull. 38:147-150 (2015) |
| 176) |
Hasegawa C, Ikaga R, Namekata I, Tanaka H, Iida-Tanaka N. The role of mitochondria on the formation of lipid droplets in adipocytes: Live cell imaging of mitochondria and lipid droplets. Int. J. Hum.Cult. Stud. 25:268-270 (2015) |
2014
| 175) |
Hamaguchi S, Kaneko M, Hashimoto R, Tamura
M, Namekata I, Tanaka H, Iida-Tanaka N. Analysis
of cellular morphology by confocal microscopy and a membrane-intercalating
fluorescent dye PKH67. Int. J. Hum.Cult. Stud. 2014 24:217-221 |
| 174) |
Tanaka H, Takahashi Y,
Hamaguchi S, Iida-Tanaka N, Oka T, Nishio M, Ohtsuki A, Namekata I.
Effect of terfenadine and pentamidine on the hERG channel and its
intracellular trafficking: Combined analysis with automated voltage
clamp and confocal microscopy. Biol. Pharm. Bull. 2014 37(11):1826-1830 |
| 173) |
Okumura S, Fujita T, Cai W, Jin M, Namekata
I, Mototani Y, Jin H, Ohnuki Y, Tsuneoka Y, Kurotani R, Suita K, Kawakami
Y, Hamaguchi S, Abe T, Kiyonari, H Tsunematsu T, Bai Y, Suzuki S,
Hidaka Y, Umemura M, Ichikawa Y, Yokoyama U, Sato M, Ishikawa F, Izumi-Nakaseko
H, Adachi-Akahane S, Tanaka H, Ishikawa Y. Epac1-dependent
phospholamban phosphorylation mediates the cardiac response to stresses.
J. Clin. Invest. 2014 124(6):2785-2801 |
2013
| 172) |
Hamaguchi S., Kawakami Y., Honda Y., Nemoto
K., Ayaka S., Namekata I., Tanaka H. Developmental
changes in excitation-contraction mechanisms of the mouse ventricular
myocardium as revealed by functional and confocal imaging analyses.
J. Pharmacol. Sci. 123:167-175 (2013) |
| 171) |
Namekata I., Hamaguchi S., Wakasugi Y.,
Ohara M., Hirota Y., Tanaka H., Y. Ellagic acid and
gingerol, activators of the sarco-endoplasmic reticulum Ca ATPase,
ameliorate diabetes mellitus-induced diastolic dysfunction in isolated
murine ventricular myocardia. Eur. J. Pharmacol. 706:48-55 (2013) |
| 170) |
Kitahara K., Nakamura Y., Tsuneoka Y.,
Adachi-Akahane S., Tanaka H., Yamazaki H., Takahara
A., Yamazaki J., Ikeda T., Sugiyama A. Cardiohemodynamic and electrophysiological
effects of anti-influenza drug oseltamivir in vivo and in vitro. Cardiovas.
Toxicol. 13:234-243 (2013) |
| 169) |
Takahara A., Takeda K., Hagiwara M., Tanaka
H. Electrophysiological effects of the antiarrhythmic drug
bepridil on the guinea pig pulmonary vein myocardium. Biol. Pharm.
Bull. 36:311-315 (2013) |
| 168) |
Namekata I., Kaeriyama S., Ikaga R., Tanaka
H., Iida-Tanaka N. Cellular flavoprotein fluorescence imaging
for the analysis of mitochondrial function. Int. J. Hum. Cult. Stud.
23: 305-309 (2013) |
2012
| 167) |
Takahara A., Fujiwara K., Ohtsuki A.,
Oka T., Namekata I., Tanaka H. Effects of the antitussive
drug cloperastine on ventricular repolarization in halothane-anesthetized
guinea pigs. J. Pharmacol. Sci. 120:165-175 (2012) |
| 166) |
Tsuneoka Y., Kobayashi Y., Honda Y., Namekata
I., Tanaka H. Electrical activity of the mouse pulmonary
vein myocardium. J. Pharmacol. Sci. 119:287-292 (2012) |
| 165) |
Takahara A., Takeda K., Tsuneoka Y., Hagiwara
M., Namekata I., Tanaka H. Electrophysiological effects
of the class Ic antiarrhythmic drug pilsicainide on the guinea pig
pulmonary vein myocardium. J. Pharmacol. Sci. 118:506-511 (2012) |
| 164) |
Asada Y., Li W., Terada T., Kuang X.,
Li Q., Takafumi Y., Hamaguchi S., Namekata I., Tanaka H.,
Koike K. Labdane-type diterpenoids from hairy root cultures of Coleus
forskolii. Phytochemistry 79:141-146 (2012) |
| 163) |
Yoshizawa A., Nagai S., Baba Y., Yamada
T., Matsui M., Tanaka H., Miyoshi S., Amagai M.,
Yoshikawa T., Ogawa S., Koyosu S. Autoimmunity against M2 muscarinic
acetylcholine receptor induces myocarditis and leads to a dilated
cardiomyopathy-like phenotype. Eur. J. Immunology 42:1152-1163 (2012) |
2011
| 162) |
Nouchi H., Kiryu N., Kimata M., Tsuneoka
Y., Hamaguchi S., Namekata I., Takahara A., Shigenobu K., Tanaka
H. Developmental changes in action potential prolongation by K+-channel
blockers in chick ventricle. J. Pharmacol. Sci. 115:235-238 (2011) |
| 161) |
Takahara A, Sugimoto T, Kitamura T, Takeda
K, Yayoi Tsuneoka, Namekata I, Tanaka H. Electrophysiological
and pharmacological characteristics of triggered activity elicited
in guinea-pig pulmonary vein myocardium. J. Pharmacol. Sci. 115:176-181
(2011) |
| 160) |
Namekata I., Tsuruoka N., Tsuneoka Y.,
Matsuda T., Takahara A., Tanaka Y., Suzuki T., Takahashi T., Iida-Tanaka
N., Tanaka H. Blocking effect of NIP-142 on the KCNQ1/KCNE1
channel current expressed in HEK293 cells. Biol. Pharm. Bull. 34:
153-155(2011) |
2010
| 159) |
Namekata I., Tsuneoka Y., Akiba A., Nakamura
H., Shimada H., Takahara A., Tanaka H. Intracellular calcium
and membrane potential oscillations in the guinea-pig and rat pulmonary
vein myocardium. Bioimages 18:11-22 (2010) |
| 158) |
Yamashiro K., Sasano T., Tojo K., Namekata
I., Kurokawa J., Sawada N., Suganami T., Kamei Y., Tanaka H.,
Tajima N., Utsunomiya K., Ogawa Y., Furukawa T. Role of transient
receptor potential vanilloid 2 in LPS-induced cytokine production
in macrophages. Biochem Biophys Res Commun. 398:284-289 (2010) |
| 157) |
Agata N., Kato Y., Namekata I., Takahara
A., Tanaka H., Chino D., Koike K., Tanaka Y. H2 receptor-mediated
positive inotropic effect of histamine in neonatal guinea-pig left
atria. Biol. Pharm. Bull. 33:2033-2035 (2010) |
| 156) |
Tanaka H., Namekata I., Ogawa T.,
Tsuneoka Y., Komikado C., Takahara A., Iida-Tanaka N., Izumi-Nakaseko
H., Tsuru H., Adachi-Akahane S. Effects of S(+)-efonidipine on the
rabbit sinus node action potential and calcium channel subunits Cav1.2,
Cav1.3 and Cav3.1. Eur J Pharmacol. 649:263-267 (2010) |
| 155) |
Tanaka H., Namekata I., Hamaguchi
S., Kawamura T., Masuda H., Tanaka Y., Iida-Tanaka N., Takahara A.
Effect of NIP-142 on potassium channel α-subunits Kv1.5, Kv4.2 and
Kv4.3, and mouse atrial repolarization. Biol. Pharm. Bull. 33: 138-141
(2010) |
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原著論文 最新-2020｜2019-2010｜2009-2000｜1999-1990｜1989- ｜もとのページ｜「心筋」トップ｜ページ先頭
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