東邦大学へ メディアネットセンターへ バーチャルラボラトリへ
東邦大学名誉教授
小林 芳郎

プロフィール

自己紹介


小林 芳郎
(コバヤシ ヨシロウ)

著書

スタンダード免疫学 (第2版) 丸善

この分野を学ぶためにお薦めする本

アポトーシスの科学 (山田武、大山ハルミ著) ブルーバックス

細胞の運命III 細胞の生死 (中西義信著) サイエンス社

学会

日本免疫学会、アメリカ免疫学会、日本生化学会、日本薬学会、日本癌学会

日本マクロファージ分子細胞生物学研究会(幹事)

日本アポトーシス研究会(運営委員)


論文(最近5年間) 2005年8月現在

Gotoh M., Takamoto Y., Kurosaka K., Masuda J., Ida M., Satoh A., Takayama E., Kojima-Aikawa K., Kobayashi Y. and Matsumoto I.: Annexins I and IV inhibit Staphylococcus aureus attachment to human macrophages. Immunology Letters 98, 297-302 (2005)

Hatada, S., Ohta, T. Shiratsuchi, Y., Hatano, M. and Kobayashi, Y.: A novel accessory role of neutrophils in Concanavalin A-induced hepatitis. Cell. Immunol. 233, 23-29 (2005)

Saijo, S., Nagata, K., Nakano, Y., Tobe, T. and Kobayashi, Y.: Inhibition by adiponectin of IL-8 production by human macrophages upon coculturing with late apoptotic cells. . Biochem Biophys Res Commun 334, 1180-1183 (2005)

Iyoda, T., Nagata, K., Akashi, M. and Kobayashi, Y.: Neutrophils accelerate macrophage-mediated digestion of apoptotic cells in vivo as well as in vitro. J. Immunol. 175, 3475-83 (2005)

Takahashi, M. and Kobayashi, Y.: Cytokine production in association with phagocytosis of apoptotic cells by immature dendritic cells. Cell. Immunol. 226, 105-115 (2003)

Ohtani, M., Kobayashi, Y. and Watanabe, N.: Gene expression in the elicitation phase of guinea pig DTH and CHS reactions. Cytokine 25, 246-253 (2004)

Takahashi M., Kurosaka K., and Kobayashi Y.: Immature dendritic cells reduce proinflammatory cytokine production by a coculture of macrophages and apoptotic cells in a cell-cell contact-dependent manner. J. Leukoc. Biol. 75, 865-873 (2004)

Iyoda T. and Kobayashi Y.: Involvement of MIP-2 and CXCR2 in neutrophil infiltration following injection of late apoptotic cells into the peritoneal cavity. Apoptosis 9, 485-493 (2004)

Kato K, Ikarashi Y, Sugahara T, Yasumoto A, Sancho D, Yoshida M, Takaue Y, Kobayashi Y, Sanchez-Madrid F, and Wakasugi H.: U5A2-13, an antigen originally found on mouse NK-like T cells, is an early inducible cell surface antigen during lymphoid activation. Cell. Immunol. 221, 27-36 (2003)

Kurosaka K, Takahashi M, Watanabe N, and Kobayashi Y.: Silent cleanup of very early apoptotic cells by macrophages. J. Immunol. 171, 4672-4679 (2003)

Saito S, Sawai K, Ugai H, Moriyasu S, Minamihashi A, Yamamoto Y, Hirayama H Kageyama S, Pan J, Murata T, Kobayashi Y, Obata Y, and Yokoyama K.: Generation of cloned calves and transgenic chimeric embryo from bovine embryonic stem-like cells. Biochem Biophys Res Commun 309, 104-113 (2003)

Kurosaka K., Takahashi M., and Kobayashi Y.: Activation of extracellular signal-regulated kinase 1/2 is involved in production of CXC-chemokine by macrophages during phagocytosis of late apoptotic cells. Biochem Biophys Res Commun 306, 1070-74 (2003)

Nishimura, M., Kakinuma, S., Yamamoto, D., Kobayashi, Y., Suzuki, G., Sado, T., and Shimada, Y.: Elevated interleukin-9 receptor expression and response to interleukins-9 and -7 in thymocytes during radiation-induced T-cell lymphomagenesis in B6C3F1 mice. J. Cell Physiol. 198, 82-90 (2003)

Mizuta, H., Watanabe, S., Sakurai, Y., Nishiyama, K., Furuta, T., Kobayashi, Y., and Iwamura, M.: Design, synthesis, photochemical properties and cytotoxic activities of water-soluble caged L-leucyl-L-leucine methyl esters that control apoptosis of immune cells. Bioorganic & Medicinal Chem. 10, 675-683 (2002)

Kurosaka, K., Watanabe, N., and Kobayashi, Y.: Potentiation by human serum of anti-inflammatory cytokine production by human macrophages in response to apoptotic cells. J. Leukoc. Biol. 71, 950-956 (2002)

Dong H, Toyoda N, Yoneyama H, Kurachi M, Kasahara T, Kobayashi Y, Inadera H, Hashimoto S, and Matsushima K.: Gene expression profile analysis of the mouse liver during bacteria-induced fulminant hepatitis by a cDNA microarray system. Biochem Biophys Res Commun 298, 675-86 (2002)

Yang, De, Nakada-Tsukui, K., Ohtani, M., Goto, R., Yoshimura, T., Kobayashi, Y. and Watanabe, N.: Identification and Cloning of Genes Associated with the Guinea Pig Skin Delayed-Type Hypersensitivity Reaction. J. Biochem. 129, 561-568 (2001)

Misawa, R., Kawagishi, C., Watanabe, N., and Kobayashi, Y. : Infiltration of neutrophils following injection of apoptotic cells into the peritoneal cavity. Apoptosis 6, 411-417 (2001)

Kurosaka, K., Watanabe, N., and Kobayashi, Y.: Production of pro-inflammatory cytokines by resident tissue macrophages after phagocytosis of apoptotic cells. Cell Immunol.211, 1-7 (2001)

Kawagishi, C., Kurosaka, K., Watanabe, N., and Kobayashi, Y.: Cytokine production by macrophages in association with phagocytosis of etoposide-treated P388 cells in vitro and in vivo. BBA 1541, 221-230 (2001)

BACK ・ HOME  ・ NEXT